Chemical Sensitisation

 Chemical Sensitisation, is thought to occur in some individuals who have high exposures to certain chemicals, particularly during a period of high stress.  Once sensitised, a person will generally react to a substance in an allergic like way, from exposures that are generally harmless and well tolerated by most. 
Chemical Sensitisation /chemical sensitivity has been linked to CIRS, Chronic Fatigue Syndrome and is experienced by some people with fibromyalgia



A sensitizing reaction is the result of a response from the body’s immune system to the presence of a chemical or biologic agent. Unlike a toxic chemical, a sensitizing chemical or biologic agent does not cause harm unless there is a reaction from a person’s immune system. One of the common immune system responses that result from a sentizing or allergic reaction is known as “hay fever.” Some chemicals may not be toxic, but can cause sensitizing reactions upon exposure. These are called sensitizers or allergens. Examples of sensitizing chemicals include: latex rubber, metals (i.e., nickel, chromium, beryllium, cobalt, etc.), formaldehyde, isocyanates, toluene, etc. Individuals who react to sensitizers are said to have a sensitivity to a particular allergen. Some chemicals can be toxic and can also be sensitizers. – –

Some articles about chemical allergies and sensitiastion

  • Key Concepts: Chemical Sensitization Michael D. Lebowitz
  • Toxic vs. Sensitizing Reactions

  • Studies reveal possible chemical sensitisation mechanisms –
  • Effects of Skin contact with chemicals (how this relates to sensitisation, skin and other organs)
  • The Role of the Brain and Mast Cells in MCS by Gunnar Heuser, MD, PhD, FACP

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