Mast Cells are part of the immune system. They help the body defend itselfs against invaders and threats. When a person has too many mast cells, too much histamine and other chemicals are released into the body, causing a wide range of allergic like symptoms. This is Mastocytosis. It is rare.
When the mast cells are over responding to threats and invaders (e.g. pathogens, chemicals, toxins) this is know as a Mast Cell Activation Syndrome (MCAS). This is more common than mastocytosis. Like Mastocytosis, MCAS also causes wide spread symptoms. In fact symptoms can be the same. Symptoms can vary from person to person. A subset of people with Mast Cell Disorders experience Anaphylaxis
Signs and Symptoms
Each MCAS patient has a unique set of triggers that cause their mast cells to degranulate. These triggers are shared in common by many MCAS sufferers and include physical factors such as temperature changes, friction, exercise, fever, emotional stress, alcohol, drugs (NSAIDS, Opioids), chemicals, scents and high histamine foods. Some patients are susceptible to some or all of these well known mast cell triggers and they are well aware of them, while other patients do not seem to know what is triggering their mast cells to degranulate. The best way for a MCAS patient to identify and remember their triggers is to maintain an ongoing record, updating it as needed.
The information at this site is for your consideration only. It is not intended to replace proper diagnosis and treatment guidance from a health professional. This is not medical advise.
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